Strigolactones are phytohormones playing pleiotropic roles in plant growth and development.^[1] Canonical strigolactones contain a tricyclic ring system and several synthetic approaches have been disclosed. In contrast, non-canonical strigolactones do not contain this tricyclic structural motive and their synthetic access has been so far limited. We report an efficient synthetic access to this novel class of strigolactones.    

[1] Claudio Screpanti, Raymonde Fonné-Pfister, Alexandre Lumbroso, Stefano Rendine, Mathilde Lachia, Alain De Mesmaeker, Bioorg. Med. Chem. Lett. 2016, 26, 2392-2400.